1) Identification of Infectious Disease Processes (22 items)
2) Surveillance and Epidemiologic Investigation (22 items)
a. Design of Surveillance Systems
b. Collection and Compilation of Surveillance Data
c. Interpretation of Surveillance Data
d. Outbreak Investigation
3) Preventing/Controlling the Transmission of Infectious Agents (22 items)
4) Employee/Occupational Health (11 items)
5) Management and Communication (14 items)
a. Planning the Infection Prevention Program
b. Communication
c. Quality Performance Improvement and Patient Safety
6) Education and Research (12 items)
a. Education
b. Research
7) Environment of Care (14 items)
8) Cleaning, Disinfection, Sterilization of Medical Devices and Equipment (18 items)
This content outline reflects the results of the Practice Analysis conducted in 2021. The Long-Term Care examination will cover the topics listed in the outline below. This list is not exhaustive and is only meant to be used as an overall guide to help direct applicants’ preparation. Download a PDF.
a. Ethics
1. Basic ethical principles
2. Resident rights and hierarchy of practices for isolation precautions (e.g., precautions are used in the least restrictive way, resident privacy)
b. Communal Gatherings
1. Impact of interaction on psychosocial well-being
2. Infection risk associated with communal gatherings
c. Interdisciplinary Team
1. Infection risk associated with facility and care team demographics (e.g., staff composition, visitors, contracted staff, staffing turnover, ratio of licensed and unlicensed caregivers)
d. Normal Aging Processes
1. Physiology and immune system changes throughout the lifespan
2. Pathophysiology and the disease process (e.g., urinary tract, respiratory, skin and soft tissue, gastrointestinal, bloodborne, viral illnesses)
e. Special Populations
1. Infection risks of complex populations (e.g., residents with medical devices, on dialysis, who need memory support, have cognitive impairment, are on respite or hospice care)
a. Infection Prevention Plan
1. Components of an infection prevention plan (e.g., regulatory and advisory requirements, facility demographics)
2. Emergency preparedness (e.g., mitigation, preparedness, response, recovery)
3. Risk assessments (e.g., how to complete and incorporate into plan)
b. Policies and Procedures
1. Best practices per regulatory and advisory agencies
2. Implementation science (e.g., key stakeholders, staff buy-in, dissemination, accessibility, feasibility)
c. Education and Training
1. Adult learning principles (e.g., communication techniques, just-in-time training, in-services)
2. Competency assessment (e.g., return demonstration, post tests, auditing)
d. Research
1. Literature review process
2. Research study design (e.g., peer reviewed, experimental vs. non-experimental, qualitative vs. quantitative)
3. Basic statistics (e.g., p value, confidence interval, appropriateness of test)
e. Quality Assurance and Performance Improvement
1. Performance improvement concepts (e.g., Failure Mode and Effects Analysis [FMEA], Plan Do Study Act [PDSA], Root Cause Analysis [RCA])
2. Performance indicators to achieve key outcomes
3. Culture of safety (e.g., reduce Healthcare-Associated Infections [HAIs], hand hygiene champions)
4. Product and process evaluation (e.g., cost benefit assessments, efficacy studies, standardization of products and processes)
f. Leadership
1. Leadership styles and principles
2. Professional development (e.g., seek knowledge, certifications, continuing education courses)
a. Clinical Signs, Symptoms, and Risk Factors to Identify Possible Infectious Diseases
1. Clinical signs, symptoms, and risk factors to identify possible infectious diseases
b. Diagnostic, Radiologic, Procedural, and Laboratory Reports
1. Interpretation of diagnostic, radiologic, procedural, and laboratory reports (e.g., chest x-ray reports, culture and sensitivity)
c. Specimen Collection, Transportation, Handling, and Storage
1. Methods of specimen collection, transportation, handling, and storage
d. Basic Microbiology
1. Basic microbiology terminology (e.g., bacteria, virus, Gram stain)
2. Microbial pathogenicity and host response
e. Epidemiologically Significant Organisms
1. Epidemiologically significant organisms, including Multidrug Resistant Organisms (MDROs) (e.g., susceptibility pattern interpretation)
2. Appropriate interventions (e.g., precautions, appropriateness of antimicrobial selection)
a. General Principles of Epidemiology
1. Basic epidemiology
2. Processes for preventing and mitigating transmission (e.g., cleaning, disinfection, vaccination, transmission-based precautions)
b. Surveillance Design
1. Surveillance methods and purpose (e.g., prospective, retrospective, targeted/priority directed)
2. Collection and compilation of surveillance data
3. Surveillance plan components (e.g., goals and objectives identified from the risk assessment)
c. Outbreak Management
1. Outbreak management concepts (e.g., case definition, period of investigation, case finding methods)
2. Outbreak management steps (e.g., reporting, control measures)
d. Collaboration with Internal and External Agencies
1. Internal organizational structure and culture
2. Public health guidelines for infection prevention
3. Public health resources and agencies for infection prevention
e. Reporting
1. Reporting structure (e.g., internal, governmental, and regulatory agencies)
f. Data Management, Analysis, and, Interpretation
1. Standardized definitions (e.g., surveillance or case definitions)
2. Data analysis (e.g., incidence/prevalence, provider specific, unit specific, device specific, procedure specific)
3. Data collection methods
4. Report preparation and presentation
5. Surveillance driven action plans
5. Prevention and Control of Infectious and Communicable Diseases (22 items)
a. Hand Hygiene
1. Key elements for a hand hygiene program
b. Standard and Transmission-Based Precautions
1. Standard and transmission-based precautions
2. Injection safety and safe disposal (e.g., multidose vials, IV medication, glucometers, insulin pens)
c. Personal Protective Equipment (PPE)
1. Appropriate use of Personal Protective Equipment (PPE) (e.g., selection, procurement, donning and doffing, point of care risk assessment)
2. Regulatory requirements associated with Personal Protective Equipment (PPE) supplies (e.g., Centers for Medicare and Medicaid Services [CMS], Occupational Safety and Health Administration [OSHA], National Institute for Occupational and Safety Health [NIOSH], Food and Drug Administration [FDA], Health Canada)
d. Food Safety
1. Safe food handling (e.g., regulatory requirements, Hazard Analysis and Critical Control Point [HACCP])
e. Resident Immunizations
1. Immunization recommendations for residents
f. Ancillary Services
1. Infection prevention practices required for ancillary services (e.g., podiatry, dental, environmental services)
6. Environment of Care (16 items)
a. Environmental Safety
1. Safe care environment (e.g., management of ventilation, water, waste, laundry; environmental cleaning; infestation; pets)
2. Environmental cleaning and disinfection practices and technologies
3. Environmental pathogens (e.g., Legionella, Aspergillus)
b. Construction and Maintenance
1. Infection risks associated with construction and maintenance (e.g., Infection Control Risk Assessment [ICRA])
2. Risk mitigation strategies (e.g., barriers, change air flow, move residents, Personal Protective Equipment [PPE] for maintenance/construction staff)
7. Cleaning, Disinfection, Sterilization of Medical Devices and Equipment (13 items)
a. Cleaning, Disinfection, and Sterilization Practices
1. Cleaning, disinfection, and sterilization practices based on intended use (e.g., Spaulding classification)
2. Cleaning, disinfection, and sterilization methods (e.g., UV light, autoclave sterilizer, disinfectant solutions)
8. Antimicrobial Stewardship (9 items)
a. Core Elements of Antimicrobial Stewardship
1. Core elements of antimicrobial stewardship in Long-Term Care
2. Antimicrobial susceptibility (e.g., antibiogram, antimicrobial resistance patterns)
3. Antimicrobials (e.g., prophylactic, empiric, and therapeutic uses of antimicrobials; broad and narrow spectrum)
b. Colonization, Infection, and Contamination
1. Colonization, infection, and contamination
2. Appropriate antimicrobial use (e.g., overuse harm, risks, ability to treat)
3. Diagnostic stewardship (e.g., no urinalysis [UA]/culture asymptomatic resident, standardized Situation Background Assessment Recommendation [SBAR] forms)
9. Employee/Occupational Health (8 items)
a. Occupational Exposure
1. Occupational exposure, infections, and infectious diseases (e.g., management, treatment, risks)
2. Requirements for compliance with regulatory and advisory agencies (e.g., respiratory protection programs, sharps safety)
b. Fitness for Duty
1. Work restrictions associated with communicable diseases (e.g., exposure, illness, compliance with Personal Protective Equipment [PPE] procedures)
c. Employee Immunizations
1. Immunization recommendations for staff
This content outline reflects the results of the Practice Analysis conducted in 2025. Starting May 22, 2026, the a-IPC™ examination will cover the topics listed in the outline below. This list is not exhaustive and is only meant to be used as an overall guide to help direct candidates’ preparation. The a-IPC™ is an objective, multiple-choice examination consisting of 100 questions. 85 of these questions are used in computing the score.
1. Processes to Identify Infectious Diseases (14 items)
a. Identification, Transmission, and Stewardship
2. Surveillance and Epidemiologic Investigation (17 items)
a. Design of Surveillance Systems
b. Collection and Compilation of Data
c. Interpretation of Data
d. Outbreak and Exposure Investigation
3. Preventing/Controlling the Transmission of Infectious Agents (14 items)
a. Standard Precautions
b. Transmission-Based Precautions
c. Antimicrobial Stewardship
d. Emergency Preparedness and Management
4. Employee/Occupational Health (7 items)
a. Infection Prevention
5. Management and Communication of the Infection Prevention Program (7 items)
a. Quality and Performance Improvement
b. Communication
6. Education and Research (6 items)
a. Education
b. Research
7. Environment of Care (10 items)
a. Environmental Safety
b. Construction and Renovation
8. Cleaning, Disinfection, Sterilization of Medical Devices and Equipment (10 items)
a. Reprocessing Practices
References have been categorized as primary and secondary sources for content information. Most questions are based on material in the primary references. Secondary references may be useful to help clarify more detailed issues in specific practice settings or content areas such as microbiology.
References have been categorized as primary and secondary sources for content information. Most questions are based on material in the primary references. Secondary references may be useful to help clarify more detailed issues in specific practice settings or content areas such as microbiology.
The following sample questions have not appeared on previous editions of the exam and have not undergone the full test development process. These are provided to APIC as examples of the types of questions included on the exam, but do not necessarily represent current test criteria or the level of difficulty.
Identification of Infectious Disease Processes
1. Koplik spots are a symptom that is specific to which of the following viruses:
a. Varicella
b. Rubella
c. Rubeola
d. Coxsackievirus
Correct answer is c
Pinkbook of Vaccine Preventable Diseases
APIC Text Online: Measles, Mumps, Rubella (Chapter 88)
2. Anti-HBc indicates
a. A false laboratory result.
b. Status as a Hepatitis B carrier.
c. New or previous infection with Hepatitis B.
d. Prior immunization with Hepatitis B vaccine.
Correct answer is c
Pinkbook of Vaccine Preventable Diseases
3. The primary serologic marker of a recent infection or vaccination include:
a. IgG
b. IgM
c. IgA
d. IgC
Correct answer: b
Pinkbook of Vaccine Preventable Diseases
4. A gram stain of cerebrospinal fluid showing gram negative diplococci strongly suggest which of the following:
a. Aseptic Meningitis
b. Pneumococcal disease
c. Meningococcal disease
d. H. influenzae disease
Correct answer: c
Pinkbook of Vaccine Preventable Diseases
APIC Text Online: Neisseria meningitidis (Chapter 89)
Surveillance and Epidemiologic Investigation
5. Prior to investigating an outbreak, the first step would be to:
a. Develop a case definition.
b. Begin case finding.
c. Confirm the outbreak.
d. Notify senior leadership.
Correct answer: c
APIC Text Online: Surveillance (Chapter 11) and Outbreak Investigations (Chapter 12)
6. Surveillance is defined as
a. Systematic collection of data for reporting.
b. Focused data collection to detect problems.
c. Targeted collection of data for quality assurance.
d. Systematic collection of data for planning, implementation, and evaluation.
Correct answer: d
APIC Text Online: Surveillance (Chapter 11)
7. Endemic infections are those infections that occur in a population:
a. Rarely.
b. at a usual rate.
c. at a higher-than-normal rate.
d. that has never been affected by them before.
Correct answer: b
APIC Text Online: Surveillance (Chapter 11)
8. Pandemic infections are those that occur
a. In a narrow geographic area.
b. In a single country affecting many people.
c. Among a previously unaffected population.
d. In a widespread geographic area affecting much of the population.
Correct answer: d
APIC Text Online: Surveillance (Chapter 11)
Preventing/Controlling the Transmission of Infectious Agents
9. Virulence describes:
a. The reservoir of an organism.
b. A factor related to a disease host.
c. The ability of an organism to invade a host and cause disease.
d. The ease with which an organism can be killed/inactivated by disinfectants.
Correct answer: c
APIC Text Online: Risk Factors Facilitating Transmission of Infectious Agents (Chapter 22)
10. The Advisory Committee on Immunization Practices (ACIP) recommends which of the following vaccines for all persons over the age 65?
a. MMR
b. TDaP
c. Varicella
d. Pneumococcal
Correct answer: d
APIC Text Online: Long-Term Care (Chapter 62)
11. Important interventions to prevent central line-associated bloodstream infections include:
a. Ensuring that central lines are rotated periodically.
b. Ensuring all central lines are inserted in a procedure room.
c. Ensuring that skin is cleansed with iodophor prior to insertion.
d. Evaluating products to ensure all needed supplies are contained within insertion kits.
Correct answer: d
APIC Text Online: Vascular Access Device-Associated Infections (Chapter 35)
12. Important interventions to prevent catheter-associated urinary tract infections include:
a. Regularly changing urine collection bags.
b. Obtaining a urine culture when a foul odor is present.
c. Obtaining a urine culture urine when pyuria is noted.
d. Ensuring urinary catheters are inserted for appropriate indications.
Correct answer: d
APIC Text Online: Urinary Tract Infections (Chapter 34)
Employee and Occupational Health
13. Elements of an Occupational Health program include:
a. Surveillance of patient illnesses.
b. Education of personnel about their risk of disease acquisition.
c. Investigation of patients exposed to ill healthcare personnel.
d. Notification of patients exposed to ill healthcare personnel.
Correct answer b
APIC Text Online: Occupational Health (Chapter 102)
14. A pregnant healthcare worker with previous history of varicella vaccination is assigned to care for an individual with disseminated shingles. She should:
a. be reassigned to care for other patients.
b. utilize Standard/Routine, Contact and Airborne Precautions while caring for the patient.
c. receive an additional varicella vaccine during pregnancy.
d. be advised to consult with her provider about potential exposure.
Correct answer b
CDC. Guidelines for Isolation Precautions.
Management and Communication
15. Competence may be thought of as:
a. the process of teaching a skill to a learner.
b. the ability to put knowledge into action.
c. the process of attaining knowledge and skill.
d. the ability to identify problems in the workplace.
Correct answer: b
APIC Text Online: Competency and Certification of Infection Preventionists (Chapter 2)
16. According to the APIC Competency Model the Early Novice IP should follow competency in all the following except:
a. Reviewing policies to guide practices.
b. Learning the basics of epidemiology.
c. Performing advanced analysis of statistics.
d. Participating in ongoing learning opportunities.
Correct answer c
APIC Text Online: Competency and Certification of Infection Preventionists (Chapter 2)
Education and Research
17. The most basic goal of infection prevention education is:
a. Ensuring knowledge of policies and procedures.
b. Identifying risk for disease transmission.
c. Developing competency in infection prevention.
d. Developing evidence-based procedures.
Correct answer c
APIC Text Chapter 3 – Key Concepts
18. A competency statement describes:
a. Responsible personnel.
b. Steps in a psychomotor skill.
c. Recommended performance measures.
d. Worker skill, knowledge, and mind set needed to perform a duty.
Correct answer d
APIC Text Online: Key Concepts (Chapter 3)
Environment of Care
19. Infection preventionists should review which of the following when assessing the environment of care?
a. Outdoor air quality.
b. Weather related outdoor humidity.
c. Air pressure relationships within the facility.
d. Elevation of the head of the bed for patients on ventilators.
Correct answer c
CDC Environmental Infection Control Guidelines
APIC Text Online: Heating, Ventilation, and Air Conditioning (Chapter 116)
20. The temperature of cold food storage (e.g., refrigerators) is monitored and recorded every 4 hours. When reviewing the temperature log the IP notes that the refrigerator temperature has been recorded as being 45 degrees Fahrenheit for the previous 16 hours. What action should be taken first?
a. No action is needed.
b. A work order to fix the refrigerator should be placed.
c. Discard food that has not been maintained at proper temperatures.
d. Determine if the temperature is being recorded after the refrigerator doors have been open for restocking.
Correct answer c
APIC Text Online: Nutrition Services (Chapter 111)
Cleaning, Sterilization, and Disinfection
21. Critical items, according to the Spaulding Classification, are those that:
a. Contact mucous membranes.
b. Contact normally sterile body sites.
c. Must be high-level disinfected.
d. Include surfaces in critical care units and surgery.
Correct answer b
APIC Text Online: Cleaning, Disinfection, and Sterilization (Chapter 31)
22. Cleaning is defined as:
a. Removal of organic material.
b. Applying sporicidal solutions to surfaces.
c. Inactivation and killing of microorganisms.
d. Activities that achieve the absence of pathogenic levels of microorganisms.
Correct answer a
APIC Text Online: Cleaning, Disinfection, and Sterilization (Chapter 31)